Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today announced that the Phase 3 investigational study evaluating dupilumab in adults and adolescents with severe, steroid-dependent asthma met its primary endpoint and key secondary endpoints.
AstraZeneca and its partner Amgen Inc. (Amgen) announced that the US Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation for tezepelumab in patients with severe asthma, without an eosinophilic phenotype, who are receiving inhaled corticosteroids/long-acting beta2-agonists with or without oral corticosteroids and additional asthma controllers.
For people with severe asthma, medicines may not help keep their asthma under control. A procedure called bronchial thermoplasty may offer relief, reducing asthma episodes or attacks in people with severe asthma.
Lexi Larabee, who has severe asthma, is currently undergoing bronchial thermoplasty. Lexi shares her experience in her own words.
I am 9 months out from my final BT! I have been OFF the prednisone since May 3rd and NO asthma spells. I have had several colds and upper respiratory infections and normally I would’ve been hospitalized due to flare ups but none! I just ran my first 5k this past weekend!! I have never been healthy enough to do so in my 24yr of life & it was the coolest and best feeling in the world! I’m also down 30lb from no steroids!
Earlier this year, we asked you to tell us about your life with asthma in our My Life With Asthma online survey. Your responses gave us insight into your unique experiences with asthma.
Asthma is a chronic condition that can be different for each person. This means there is no “one size fits all” approach to managing asthma. Many people manage it well with the right treatment. But 5 to 10 percent have trouble even on maximum treatment. These people have severe asthma.
What I really find annoying about asthma is it robs me of being able to have a good belly laugh...I starting coughing and lose my breath. So because people don't see me laugh too much they think I'm a crab!!!
It’s obvious that asthma affects your health. But how does it impact other areas of your life? The results of our My Life With Asthma online survey showed us how severe asthma can affect relationships, emotions and activities.
@Marie E Natzke , laughter is one of my biggest asthma triggers. It stinks because I consider myself to have a great sense of humor and I'm the type who laughs so hard I have tears streaming down my face. But it comes at a cost, every time.
What I dont like about it is that it made me feel less important to people than their pets and that for many years I also treated myself that way and put myself around animals that made me suffer so badly until I had a heart attack due to allergic eosinophils surrounding my heart and choking it, then I took it seriously but still others dont and I struggle to stay strong and remember what happened to me so that that never happens to me again and its difficult because friends get dogs and I...
Severe ASTHMA (Asthma Symptoms, Treatment, Health Management and Activities™) Care for Adults is a FREE self-paced course that helps adults and their caregivers learn how to manage severe asthma. It explains severe and uncontrolled asthma, the impact of severe asthma, asthma management plans and severe asthma treatments.
I underwent my second Bronchial Thermoplasty on October 4th, 2018. My recovery from BT 2 was a bit longer than the first procedure because my left side is weaker than my right. I was back to work though after 5 days off and back to my everyday life. I just had my third and final procedure done and being day 1 it has been ROUGH. my ribs feel like they're all cracked, I get winded just sitting up in bed but this is all expected and normal. I just keep telling myself it will all pay off in the...
Update: 5 months out from my final procedure. I have had two upper respiratory infections and one right now as I’m typing this. I have been able to stay out of the hospital and only had to bump up to 20mg steroids instead of 80mg. I normally would’ve been admitted to the hospital until this passes. I’m still having bumps in the road but I would say I’m doing amazing! My first Michigan winter NOT going to the hospital!!!
The Asthma and Allergy Foundation of America is sharing this press release from GlaxoSmithKline to bring you the latest research news quickly. [PRESS RELEASE] Nucala (mepolizumab) study reports long-term safety data, consistent exacerbation reduction and improved asthma control New study showed one third of patients had no exacerbations on long-term treatment with Nucala GlaxoSmithKline plc (GSK) today presented new data from the longest study of an anti-IL5 biologic treatment in severe...
The FDA has approved another biologic treatment, Dupixent, for the treatment of both moderate and severe asthma patients with eosinophilic phenotype
and oral corticosteroid-dependent asthma, regardless of phenotype.
Circassia Pharmaceuticals, Inc. (“Circassia” or “the Company”), a specialty pharmaceutical company focused on respiratory disease, today announced that Fractional Exhaled Nitric Oxide (FeNO) monitoring is recommended in the latest Global Initiative for Asthma (GINA) guide, “Difficult-to-Treat & Severe Asthma in Adolescent and Adult Patients – Diagnosis and Management.”
Lexi Larabee, who has severe asthma, had bronchial thermoplasty one year ago and shared her experience with the Asthma and Allergy Foundation of America (AAFA). Below, Lexi tells us what her life has been like after the procedure.
Asthma is a chronic lung disease where the airways are inflamed. For many people, asthma can be controlled with medicines and avoiding triggers. But severe asthma is not that simple. How do you know if you have severe asthma?
Hi, Tomek, You can control the level of emails you receive from our community. Take a moment and update your preferences to see just what you want to see. Hover over your user name and then select "Notifications." If you are on a mobile device, click the menu icon (3 horizontal bars) on the left to pop out the menu. Then click on your user name, then "Notifications." If you are having trouble finding it, use this link . You can choose to be notified of AAFA blog posts, events, when someone...
When you block a person, they can no longer invite you to a private message or post to your profile wall. Replies and comments they make will be collapsed/hidden by default. Finally, you'll never receive email notifications about content they create or likes they designate for your content.
Note: if you proceed, you will no longer be following .