While I know that I am in the tiny percentage of the population who has a strong negative reaction to the Methacholine Challenge test, I want to offer one caveat. About six years ago, I had chronic cough and my doctor thought I might have asthma so he had me take the Methacholine Challenge test. Taking the test turned my, as yet unknown, asthma into moderate-to-severe persistent asthma. Hope no one else has this experience but it is something to consider.
I've had things I knew I was allergic come up negative on blood tests but positive on skin prick tests and obviously positive when exposed to the allergen. From what I understand there is a difference in allergic responses that isn't always picked up on blood tests, and also that sometimes an allergen has more allergenic components in it than what is looked for on a specific ige blood test but that do often pick up on the skin prick test. I have also heard some allergic reactions are more...
@Shea is absolutely right -- a reaction can indeed occur immediately or 2 - 6 hours (sometimes more) later . Seeing a board-certified allergist is definitely a way to get a more accurate assessment of what your allergies truly are.
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